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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '060a5641c551be99c40cb5aa385bf7d7e18be1175110d22074e4b7542101e90d' 
  AND token = 'tNa68lbvQ1FfDrfWozUHVZF9wMpKMDpw6l2Nq+CVo38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}