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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8280f51ee45ad7416065a59b8656e59f0e9162bda8e40b88927d57129d4a8c12' 
  AND token = '+ZMf4mQojU1LygXDO96Qxchs9xDx5jCmQBip/aYyBYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}