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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef967f35a30e23b7900845492345876f339c3633915d05a5c895f583012ce623' 
  AND token = 'vJisIq/l15+RaZqMre6PmHacS7C9pzb9bJHqZ39s0mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}