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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d1e2b71dd8c14d96412b02cf733b9edd0f838234369ef7f028b7a125a71de6' 
  AND token = 'oG2eBy3aRwAjk1A6GZLRAuAF1YbgK51oYNCUcXxB8sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}