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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd915bf07f1c5c7210013cd903ada1e07264dede2a6c67304076f706c45c3ce74' 
  AND token = 'WLHxYVVMs3DQBgsd1KS2iRHrw253H+WGL55YiGIFvko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}