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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35f66c0f1d9d2bb6a1fc89df10da86ab64a82239bac70e2f609f699a11dfac21' 
  AND token = '2+ANNGgFLdfE1HC3KCUlr5vpFC0MAxy+yHbQ8lhSdBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}