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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1620f5b848be0d84e1aba9f7cc7bfb7d67f74758a35f584dbcfac722c957826' 
  AND token = 'WT+r+JMdZPeNK8Y01Wk19sRzciS9duQ1KNOCuiOqBzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}