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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f263e3c0639e01183f464b87e072edc1b9400c30262c1b46f93663e262d0d2e0' 
  AND token = '5yiWy6ZSog3Lrmoky3/xJ7z4OJGV90RNFLf0EK5Cx6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}