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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e035f3760f0ee5b286a844a868aa8c9ce4a2de801be60a93e25e5ada8bd823' 
  AND token = 'a+xn/m77Z+/02OyThDEmpDGRrs9ceLIGnZrF/XDw8MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}