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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900e8b18ec9c3e52a465043da933a5c054dc8465305c14f04ceeaf2187cb38f3' 
  AND token = '52dMDt4+Kgq7pl78FVmgEO+XqAbjG8GgZUpLFHUL6HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}