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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f45daaa672468f23b8d628b3d5bf099debf52eb0c3de99a1bd80c64f21ce46' 
  AND token = 'P4mJx4TWth+Tc683eXn3VlZBwJO2QJzlakKc1OhXzuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}