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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f3d9218d8975bf570f9de6bd7f5fedabf7621e3f67875925e4e793c32d0a74' 
  AND token = 'prCwvfN87YT3F2DMz3Nr4hbIATGraeHTqaAn7bWng7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}