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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e826fa769de307a10300bd076f2d2b85ca19c2f7b09b199ea854f7e10dd9f57b' 
  AND token = '1wMdWNH20LBvUvzEi0+dn7v5UjsLiQx4N1mMVblIc3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}