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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa275a2d4fba3581c75336ee36459ade5310311bf0e48658be7304b5e0df7534' 
  AND token = 'Y2eeAP5RK663tx/yklZ6FN3zlq2KUYdC7Y8uT2GkAs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}