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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2961361527d0a72d5713367acfc74312d4fb2aa2e396b254ec38758d0a4809' 
  AND token = 'Mj2ofJEMlP9EcaJJKRRJWx+FxlSUj4f6ukM2AfFgB4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}