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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6454c71eddc68afb818cbcf4b0f53da9e4a168f1da1fa85604705fc4c53293' 
  AND token = '9Fu12G9Njr14shWlZDkjDvxPu8lOM7ZLDx+Sy9RVd0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}