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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439fc49582dbedc349aaae598ba1482fe0295872945f5f868fb7df0ce9be857f' 
  AND token = 'jIwnC5a6PKQTq67lwkiXvShkwW+qOrvyv2C/4fxA0hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}