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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43b0588476b9cc35ad3586599c77c21790c8aa51dfd1583686efbf539a25644' 
  AND token = 'r/THQZFfH1/7DeP+BcoD7k8Le4CoSe2SkaYpEf5w330=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}