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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2356b830247d8f03d7dec84aafba0ca34d46f50cde373e565ace5138907f366' 
  AND token = 'ewNHpyFhgwFlJUhYgHWsdZTtsa3Nbv0lwBE56rF2rWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}