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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459dbcabda0d239b6ba9261e00f911ffe2e0130b53c37dd1b27298ffbede1215' 
  AND token = 'nbg/xTiSveuUwldM4iA8qPtfkADmcirB0nCKrOkmF8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}