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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7e6c43bdcb0d790fcedc107d6c42eb0862b894bd6bd5b433566d614a05f617' 
  AND token = 'uiebChMI2+IXLFOA1IMjcYZUjuJtdWOELKhg8CfKb1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}