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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8547126fc7e65b9f97dcd12f62fb88b1b2295d749f9072ac2b7d27bc65ac6735' 
  AND token = '1JBBDvcIO2ckVzaSI+T7GM9yE8+CcqCZJSDokMZxiQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}