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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce65dd8fb121a92911034fc4cb5537ee2d0d447f709b71dabb0d49f35a19edc' 
  AND token = 'nUr9LbGa1bWduJRGlfjq/gIkKTq5H6+6nSD1Pv8bnMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}