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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca497d470bd5578b095987e1b72cf0ab57edaa1e9673b544d5a8371514e12ddd' 
  AND token = '2E8Hjpi+6kaxtcJZzVmDnlGSLW+D5uISt+nUU3Ol71U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}