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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ea10d452da746acedddaefff0e87a6245e1898977ec6a6a775d1d4999ac310' 
  AND token = 'AkyvslZfkehx4s1/Cmn9UnsQ2pk24X5snt53ehwK8do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}