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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeb4fd8ee9cda46fc254e24878c340c565b300baf06b2338add37100e99b76bb' 
  AND token = '/tbtA46Y9OFK2eAm6S2Z+9TNsYhjp21UO67SRZ6Yp+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}