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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ea9e40fee09182588db60ab28e03262897c8629e8dd2fed852b7765767e323' 
  AND token = 'cwsF9trZkAFdDRKvSHgyWNZSEzg+z4Uzk9Fu2U+ft4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}