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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d86523ff1ec53075e2c555dfd3e794a45928279c77acaf2fdf1f5eaff6dbb74' 
  AND token = 'v/rnUzNv1sF7gRJ1OcpU8g1aYEv/dtpyL9uo54BU3Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}