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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10b89709ae1f9b5ca9f12d628c435ec4ed1b16097d7420a27cbdad50f223863' 
  AND token = 'yVrPs6vYupKtM+X8OH2/8NsXwq9am1PpAVSHNo4G6c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}