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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c88a421d82f74e031d277bfdbae10aab4c37876b1859623907eb957107b58ff' 
  AND token = 'hFmAzb2BCZ41X4bZ1XzPBzT/rGe98O6CCp5xzRPbV7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}