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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bc6d797e03a62b2b444eeb1a8da74efddf30704e46812c3a52c12d2512f76b' 
  AND token = 'qDz9jJGpW6RAQmexJNjenZdhLrXi+rllQPvaxbcygOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}