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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456743c2ee2031d5f7005771cb51ba49f0ec4c878d97af0b2f33a81475d6d8bb' 
  AND token = 'HdReHmqpy0WpSNClI2js4mjfUv/hIlH2CdsJPVG7F2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}