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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e5fe31a790fcc7972980b1a120ed769bca9d8431862c3b3fa0693940eae7b2' 
  AND token = 'aUuANNjz45FWVPWR9T+gnLGUb59Jv4t9OVl6HTHStZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}