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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ff1c53c51b6bd869ba7d233da8698f037c38f76747c4707917354b45009bde5' 
  AND token = 'JW447qFR0LkoeWp/gyi6xaXFdsHxhgb1jT8DhXd8UMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}