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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f666f48cb11e3bd6ffaf64a4587ac00bb151e604fa82ed59f1a3ea6135652b55' 
  AND token = 'OSV886gdSkAy6cYAEmxkDxfLy4XZwA1DKxKwYvvpzD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}