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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d4a2525d1a3f2433ed65e7875ad26989300bdf6aee39424b44d4564d91174c6' 
  AND token = '9c4ByOGrQHwtL+kOJjBnBTUdCPIuqnb5sDS2pF+9jyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}