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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad8cc9e21f462e58811fbca9da323fc15855dbfe850dab3b64a71c8d51ca2ca' 
  AND token = 'D0zggytnXZmRwpW8st+AAP9i56Iagil6IFtbtbUBmow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}