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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351860ae61001134c0241b1834609afdb3b8959ceb869c0cb796a78191c152e4' 
  AND token = 'HMoFc+1cFJyXOOWX46WE3dVCgcZCdI9BR6jBabZq+UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}