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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49543de426b0a2a5ee1bd082aae1b57872cf1b26d5bcef39fe42217298c45e0' 
  AND token = '+vqhrH7TfZ7zeRw5h+WbtqOd1GuPkQJeFzRyeFMyroA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}