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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70e75043ccc961a4b6710c6506adf24dc8b343f84da5fb2e15f174d361595710' 
  AND token = 'mSpAaXlQt8lzLytp5z6NoVft8TBCN8dD8ml/6FDdObA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}