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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f4bc3dee04b2c561c544a1e1021d49f9d8fff783aff04350fad8db08852f03' 
  AND token = 'MKptqoqytKWL7EQlOvbLQ0Creo4wuzYsrhDWjI/ie9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}