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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d5e95e524a5ff7e778c9995aceb4d83b816b0b27fb0e8157153b5989f67b4f' 
  AND token = '3jJ3aWml5sRMoIgM8VcdTBZJdbzpq6yZkqZNUFXlwJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}