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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2dd6c8310c99f9ad1ce9dd375dc0fa015050c90be7ff92d4180c59e485efd61' 
  AND token = 'FYZUkoH7AiPlfoBUuzFkaDWo/NvlP41Xi37ap1E2d0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}