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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577f379776845ddeac24f9d84edc43df9eec4f506b3b8491d2250c58b6b8493e' 
  AND token = 'iv0kfO10mzyYR8TdDOE/WPrQ1QMMk2nCTCE4YWZHcr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}