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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9f672bd9674a0dd757cee916a488a18e66011270fa5fe48ef3cc8b3fb3fd530' 
  AND token = '2jIK8PAgSBV8IUAqPWWV5uh4MUeDqeKRpD3vO3q2lKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}