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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6ac49ddf30cd57e68c45cb70442606a7effbee80c6b6cfee00435f0286097f' 
  AND token = 'NQK9/WUhmdhSx9s6ajpCOeWI7ZmEzmwcjp7TfkoU4lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}