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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a3276a69fad089c7ff0ccab7e6636750c7eebc82e3d8c4d861ffe1c5012348' 
  AND token = 'Es/wUIaf3gscJjpE+r0324VVj4wWfRWK0/QKvNceWL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}