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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84e33a1d8591ecac8cdc2babb7c9980a25b3bc46949dfa09dcfc50d44cd5a576' 
  AND token = 'ymx/uoLAxQTdjUj/9c3YoJJl4Lm20kGb0MA6sGu+YDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}