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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b222cdba189b03634d2a2d66df4e49ad780e3a731ad61a2b1f79a050a68dca' 
  AND token = 'tYtlj1ca3KmBisFSwDZiTyZo7taSM+waxoZm7kW4LEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}