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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e28bde508b306eff1077eae524f6a70593a9d24467922fa5027e2e9117a4ae2' 
  AND token = '8KBKENV5FZIOyhT8BPAESAug9UpG8sJNY5hQsajdUnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}